The WHO classification of CNS tumours is the most widely accepted system for classifying CNS tumours and was based on the histological characteristics of the tumour. Although the most recent version of the ‘blue book’ is the 4th edition from 2007, an update has been released in 2016 3, which should be considered a replacement of the earlier version. “At this point, a decision to undertake the 5th edition series of WHO Blue Books has not been made” 3. This 2016 update has, for the first time, included molecular parameters into the diagnostic schema, and in fact has elevated them in some instances above histological features 3.
This is a fairly dry article, primarily for reference. For more readable versions, see the article on brain tumours and brain tumours in infancy for general discussion of these topics.
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