People are often alarmed to hear a physician say there are “spots” on the magnetic resonance image (MRI) of their brain. These spots may be referred to as “unidentified bright objects” (UBO), “high signal intensity areas” (HSIA), “white matter hyperintensities,” and “nonspecific white matter changes.”
White matter hyperintensities are often located next to the ventricles, and as the name implies, are found in the brain’s white matter.
They are most obvious on T2 weighted scans.
How worried should people be about those white matter changes? There is no widely accepted guideline for what is “too much,” though most neurologists have their own personal opinion. Some degree of these changes is expected with age. Ignoring the lesions completely, however, is not the best course of action.
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